Intra-left ventricular electromechanical asynchrony

Prognostic value of intra-left ventricular electromechanical asynchrony in patients with hypertrophic cardiomyopathy.

AIMS We sought to assess the indexes of myocardial activation delay, using Doppler myocardial imaging (DMI), as potential predictors of cardiac events in patients with hypertrophic cardiomyopathy (HCM). The distribution and magnitude of left ventricular (LV) hypertrophy are not uniform in patients with HCM, which results in heterogeneity of regional LV systolic function. METHODS AND RESULTS T...

Noninvasive mapping of left ventricular electromechanical asynchrony by three-dimensional echocardiography and semi-automatic contour detection.

A system for analyzing left ventricular (LV) electromechanical asynchrony based on transesophageal 3-dimensional echocardiography (3-DE) and semi-automatic endocardial contour detection is described. Eighteen consecutive patients underwent 3-DE. Using TomTec 4DLV software, a 3-dimensional endocardial surface was reconstructed throughout the cardiac cycle. Matlab software generated color-coded p...

Left ventricular electromechanical mapping in stunned myocardium.

A62-year-old woman with a history of vasospastic angina presented to the emergency room with chest pain. The ECG showed ST-segment elevation in leads V3 through V6. The transthoracic echocardiogram revealed an akinetic left ventricular (LV) apical wall. The coronary angiogram on admission demonstrated normal coronary arteries. Two weeks later, resting Tc-tetrofosmin myocardial single photon emi...

Effect of dobutamine on regional diastolic left ventricular asynchrony in patients with left ventricular hypertrophy.

Dobutamine improves systolic as well as diastolic function, but its effect on left ventricular (LV) asynchrony is unknown. An on-line automated segmental motion analysis (A-SMA) system was developed, based on an automatic border detection technique, to evaluate the effect of dobutamine on LV asynchrony in patients with LV hypertrophy (LVH). Low dose (5 microg x kg (-1) x min(-1)) dobutamine str...

Left ventricular asynchrony in early isolated cardiac sarcoidosis.